by Dr Neelima Mantri | May 16, 2024 | Blog
Let’s delve into the realm of uterine sarcoma, a rare but serious form of cancer affecting the uterus. Uterine sarcoma is characterized by the uncontrolled growth of cells in the uterine tissues, which calls for prompt clinical intervention to minimize the critical implications.
Diagnosing the etiology, monitoring its symptoms, and discovering its treatment options are indeed indispensable for successful uterine sarcoma treatment and prompt recovery. Let us, together, delve into the intricacies of uterine sarcoma, examining all of the core issues, including its causes, signs and symptoms, and treatment approaches for those who deal with this situation daily.
The Causes of Uterine Sarcoma:
Genetic mutations, such as TP53 or RB1 gene alterations, may evolve uterine sarcoma. Prolonged exposure to estrogen as women taking estrogen-only hormone therapy can be also a contributory factor. Patients with HLRCC, an inherited condition, and those who have received prior pelvic radiation therapy fall in the high-risk category.
The involvement of factors like nulliparity, advanced age, and Black ethnicity cannot be ignored. The multiple factors include genetic, hormonal, and environmental elements. Identifying the risk factors is not only the key to the prevention strategies to be developed but also to early diagnosis.
The Types of Uterine Sarcoma:
The type of uterine sarcoma includes a variety of subtypes, all being unique in their morphologic features. The most predominant type of uterine sarcoma is leiomyosarcoma. It develops from the smooth muscle cells that line the uterine wall. Endometrial stromal sarcoma originates from the structural support cells or stroma cells within the endometrium.
Undifferentiated sarcoma encompasses a range of tumors that lack distinguishing cellular characterizations. Adenosarcoma, carcinosarcoma, and mixed epithelial-mesenchymal tumors are among the less common subtypes. There is a variety of clinical features, prognosis, and tailored treatment options for each subtype of uterine sarcoma, thus the correct diagnosis forms the backbone of individualized management of patients with uterine sarcoma.
Analyzing the Symptoms:
Women may experience abnormal bleeding during their menstrual cycle outside of their ovulation, which may occur after menopause, commonly associated with the onset of uterine sarcoma illness. Some individuals may feel pain or pressure in their lower abdomen area causing discomfort. Lumps in the abdomen could mean that it is a tumor.
Understanding the Diagnosis:
To diagnose uterine sarcoma a physician starts with imaging tests such as a ultrasound or MRI to examine the uterus for any abnormal changes or growths. In case these tests reveal anything abnormal a sample tissue is removed.
During this process, a little part of tissue is taken from the outside of the uterus and it is observed under a microscope. This is done to check if cancerous cells are present or not. Thus, doctors will be able to diagnose uterine sarcoma accurately and craft a carefully chosen treatment plan.
Meet Dr. Neelima Mantri, renowned as the best gynecologist in Mumbai. Through a gender-specific approach, Dr. Mantri gives attention to the health of all women, personalized care, and solutions. She is trusted by lots of people and offers fully comprehensive and professional care for all gynecological matters.
by Dr Neelima Mantri | May 8, 2024 | Blog, Women Health Issues
A Urethral Diverticulum is a rare condition where a pouch or sac forms along the urethra, the tube that carries urine from the bladder out of the body. The pouch may leak some urine, causing pain during urination, frequent urinary tract infections, and difficulty in releasing urine from the bladder. The condition mainly affects women but can occur in men as well. Infectious, traumatic, or congenital abnormalities may cause a Urethral Diverticulum.
Urethral Diverticulum Symptoms
The clinical features of a Urethral Diverticulum are pain or discomfort during urination, frequent urinary tract infections, urinary leakage between urinations, urinary urgency, and frequency. Furthermore, a patient will experience a feeling of incomplete bladder emptying.
Some might have pelvic pain, dyspareunia (pain during sexual intercourse), or observable swelling near the urethral opening. Symptoms can increase with time and become worse if left unaddressed. Early diagnosis and treatment can help combat the pain and avert the side effects.
Urethral Diverticulum Diagnosis
Diagnosing a Urethral Diverticulum is based on a careful review of medical history, thorough physical examination, and specific tests. During the physical inspection, a healthcare professional may press the skin around the urinary opening to check for any signs of pain or swelling.
However, in some cases, imaging methods like ultrasound, MRI, or voiding cystourethrogram (VCUG) may be performed to see the diverticulum and assess its size and location. Besides that, cystoscopy, where a thin tube with a camera is inserted into the urethra, may be performed to see the diverticulum and surrounding tissue directly.
These diagnostic measures confirm the presence of a Urethral Diverticulum and allow the healthcare team to decide on the best possible treatment plan.
Urethral Diverticulum Treatment
The treatment of Urethral Diverticulum varies based on the severity of the symptoms. Mild cases with negligible symptoms may be controlled with warm sitz baths, antibiotics for urinary tract infections, and bilateral urine drainage through a catheter from the verge of the diverticulum.
While conservative treatments are practicable in mild symptom cases, surgical intervention may be considered when the patient is suffering from severe or intractable symptoms.
The surgical options are of two types: diverticulectomy (removal of diverticulum) and marsupialization (creating a new opening for drainage). The surgical option is chosen based on the size of the diverticulum or the site where it has developed.
Best Gynecologist in Mumbai
Dr. Neelima Mantri is the best lady gynecologist in Mumbai, renowned for her expertise and compassionate care. Having years of practice, she specializes in diverse gynecological operations and holds a good reputation for consistently taking care of women’s health. Be sure to get in touch with expert professionals to gain detailed information on this topic.
by Dr Neelima Mantri | Apr 16, 2024 | Blog, Pregnancy Complications
When two or more fetuses are conceived, it is known as a multiple pregnancy. This condition poses special dangers and challenges for both the mother and the unborn child. Whether they are twins, triplets, or higher-order multiples, these pregnancies can result in several issues that need to be closely monitored and managed by medical specialists.
To achieve the best possible outcomes for the health of both the mother and the fetus, multiple pregnancies require specific attention and care, from gestational diabetes to premature delivery. Comprehending the possible issues linked to multiple pregnancies is essential for prompt detection, intervention, and the provision of customized medical assistance.
Maternal Health Complications
The mother’s well-being is considerably at risk due to maternal health issues that arise from multiple pregnancies. Among them are:
Increased risk of hypertension and gestational diabetes as a result of the mother’s body being under more stress.
An increased risk of preeclampsia, a potentially fatal illness marked by organ damage and elevated blood pressure.
Greater uterine enlargement and possible postpartum contraction difficulties make a woman more vulnerable to postpartum hemorrhage.
increased chance of cesarean birth, which is frequently required due to issues including placenta previa or fetal malpresentation.
Increased psychological difficulties and emotional strain brought on by the complexity of handling numerous pregnancies, including nervousness.
Delivery and Labor Considerations
Planning and handling of labor and delivery issues in multiple pregnancies must be done carefully. Among the crucial elements are:
Higher risk of preterm delivery, which calls for vigilant observation and possible measures to extend the gestational period.
Increased risk of fetal malpresentation, including transverse or breech positions, which might affect the birth method.
Possibility of difficulties that might require specialized obstetric care during labor, such as placental anomalies or cord entanglement.
A skilled medical team with experience in handling multiple pregnancies is required to guarantee safe delivery for the mother and her unborn children.
The possibility of cesarean birth owing to several reasons, such as fetal position or labor problems, necessitates cautious thought and preparation in advance.
Neonatal Care Requirements
The requirements for neonatal care are generally greater and more involved for babies delivered from multiple pregnancies than for singleton births. Numerous health issues, such as respiratory distress syndrome, low birth weight, and preterm, might affect these infants.
As a result, specialized newborn care facilities with cutting-edge equipment and qualified medical staff are crucial. When it comes to giving babies with particular requirements prompt medical treatment, breathing support, and monitoring, neonatal intensive care units (NICUs) are essential.
Close coordination between pediatricians, neonatologists, and other experts is also essential to ensuring that each infant has a thorough care plan that meets their specific medical needs and maximizes their chances of healthy development.
To protect the health and well-being of the mother and the unborn children, it is essential to comprehend the intricacies and potential issues associated with multiple pregnancies. These difficulties can be successfully overcome with the best gynecologist in Mumbai and specialized treatment and skilled management.
With her vast experience in high-risk obstetrics, Dr. Neelima Mantri is a famous gynecologist in Mumbai and she provides the knowledge and skills required to successfully manage these pregnancies and benefit both mother and child.
by Dr Neelima Mantri | Apr 12, 2024 | Blog, Pregnancy Complications
A serious pregnancy challenge known as Placenta Accreta occurs when the placenta adheres to the uterine wall too firmly and occasionally spreads to neighboring organs. This condition has to be carefully managed since it presents serious dangers to the mother and the unborn child during delivery.
Comprehending the signs, origins, and available therapies for Placenta Accreta female gynecologists in Mumbai is essential for prompt identification and suitable medical assistance to guarantee optimal results for both the mother and the kid. We will go over the warning signs and symptoms, underlying causes, and potential treatment options for Placenta Accreta in the following section.
Learning About the Symptoms
Symptoms of Placenta Accreta may vary depending on the severity of the condition. Nevertheless, frequent indicators to look out for are as follows:
Vaginal Bleeding: One of the main signs of Placenta Accreta is abnormal bleeding during pregnancy, particularly in the third trimester.
Preterm Labour: Premature contractions or labor before the due date are possible in women with Placenta Accreta.
Pelvic Discomfort: As the placenta penetrates farther into the uterine wall, persistent or severe pelvic pain, especially in the lower abdomen, may be a sign of Placenta Accreta.
Unusual Foetal Position: Because the placenta’s attachment distorts the uterus’s typical shape, Placenta Accreta can result in incorrect fetal placement, such as a breech presentation.
Anaemia: Fatigue, weakness, and other related symptoms might be brought on by excessive bleeding linked to Placenta Accreta.
The Primary Causes
Although the precise etiology of Placenta Accreta is unknown, several variables may raise the chance of getting the condition:
Past Uterine Surgery: Due to the creation of scar tissue on the uterine wall, women who have had previous uterus operations, such as cesarean sections or dilatation and curettage (D&C), are more vulnerable.
Placenta Previa: In women who have placenta previa, the placenta implants close to or above the cervix, making Placenta Accreta more prevalent.
Neonatal Care: Depending on the gestational age, premature delivery may be necessary, requiring specialized neonatal care to manage any potential complications associated with preterm birth.
Advanced Maternal age: An increased risk of Placenta Accreta is linked to older mothers, maybe as a result of alterations in the uterine lining with aging.
Multiparity: Pregnant women are more likely to become pregnant again, probably as a result of the uterus expanding and contracting with each subsequent pregnancy.
The Required Treatment
Multidisciplinary care is usually used to treat Placenta Accreta. Options include uterine artery embolization to stop bleeding, blood transfusions to treat anemia from bleeding, scheduled cesarean hysterectomy to surgically remove the uterus and placenta, conservative management with close observation for less severe cases, and specialized neonatal care if an early delivery is required.
Every strategy seeks to reduce the dangers to the mother and child, with choices depending on the patient’s unique circumstances and the severity of the ailment. For optimal results, early diagnosis and timely management are important.
In conclusion, you may rely on Dr. Neelima Mantri for skilled therapy of Placenta Accreta. Dr. Mantri provides substantial experience in high-risk obstetrics and laparoscopic surgery, having worked in obstetrics and gynecology for more than 10 years. She is one of the best gynecologists Mumbai option for thorough and caring care because of her focus on achieving positive results in difficult obstetric circumstances.
by Dr Neelima Mantri | Apr 10, 2024 | Blog, Women Health Issues
Even though postmenopausal bleeding is frequently concerning, it is a condition that needs to be recognized and understood. This bleeding can be an indicator of several underlying disorders and usually occurs after a woman has gone through menopause, which is generally described as not having menstruated for 12 consecutive months.
Endometrial cancer and uterine polyps are two more dangerous reasons that can occur in addition to more benign ones like hormone imbalances or vaginal atrophy. Effective postmenopausal bleeding management requires an understanding of the possible causes, a correct diagnosis by a gynecologist in Mumbai, and the pursuit of suitable treatment.
The Primary Causes
Hormonal Fluctuations: Variations in progesterone and estrogen levels during menopause can cause postmenopausal bleeding as well as other irregular bleeding patterns.
Vaginal Atrophy: During menopause, the vaginal walls are often thin and dry, which can lead to discomfort and bleeding.
Endometrial Atrophy: Postmenopausal bleeding may result from the weakening of the endometrial lining that happens with aging.
Endometrial Hyperplasia: Abnormal bleeding may arise from the endometrial lining being thinner as a result of exposure to too much estrogen.
Endometrial Cancer: Postmenopausal bleeding may occasionally be a sign of endometrial cancer, emphasizing the need for an immediate assessment by a doctor.
The Diagnosis
When a healthcare professional diagnoses the underlying cause of postmenopausal bleeding, it usually requires a comprehensive evaluation:
Medical History: The healthcare professional will start by obtaining a thorough medical history that includes details on the occurrence, length, and intensity of bleeding episodes.
Physical Examination: To check for any anomalies or indications of infection, a pelvic examination may be conducted.
Imaging Tests: To see the uterus, ovaries, and other pelvic tissues and find any anomalies, including polyps or tumors, imaging investigations like transvaginal ultrasound or pelvic MRI may be requested.
Endometrial Biopsy: To collect a sample for microscopic inspection and rule out endometrial cancer or other abnormalities, a biopsy of the endometrial tissue may be advised as well.
Laboratory Tests: Blood tests can be used to check for symptoms of anemia or underlying medical issues, as well as to monitor hormone levels like progesterone and estrogen.
Other Procedures: To further assess and treat the underlying cause of postmenopausal bleeding, additional operations including dilatation and curettage (D&C) or hysteroscopy (insertion of a thin, lighted tube into the uterus) may be performed in certain circumstances.
Fundamental Treatment
The underlying reason found during diagnosis determines the course of treatment for postmenopausal bleeding. Hormone replacement treatment (HRT) may be recommended to control hormone levels and treat symptoms if the bleeding is the result of fluctuating hormone levels. Surgical surgery may be required to remove abnormal growths or correct structural abnormalities, such as fibroids or polyps when seen.
Stronger therapies, including a hysterectomy or chemotherapy, may be necessary for endometrial hyperplasia or cancer. Postmenopausal bleeding symptoms can also be reduced by treating underlying medical concerns such as blood clotting or thyroid issues. The demands and medical conditions of each individual are taken into account while creating treatment regimens.
Postmenopausal bleeding needs close observation and an expedient medical assessment to determine its underlying causes and start the proper course of therapy. Renowned obstetrician, gynecologist, and laparoscopic surgeon Dr. Neelima Mantri provides thorough attention and experience in treating diseases in women’s health.
With more than ten years of expertise and specific training in high-risk obstetrics, Dr. Neelima Mantri is considered one of the best female gynecologists in Mumbai and has successfully managed many challenging scenarios, ensuring her patients’ optimal outcomes in most cases.
by Dr Neelima Mantri | Mar 11, 2024 | Blog, Women Health Issues
The cases of vaginal cancer, cervical cancer, penile cancer, and anal cancer in both men and women are increasingly prevalent worldwide. Because these cancers require invasive treatments like surgery, chemotherapy, and radiotherapy, they pose significant risks to reproductive and sexual function, even with the right treatment and care.
Fortunately, the HPV vaccine can drastically reduce the risk of these particular types of cancers, along with other types caused by the HPV virus. The HPV vaccine is one of the most effective vaccines available today, scoring the highest efficacy rating in protecting against the HPV virus. Yet, not many are aware of this cost-effective vaccine.
Today, with insights from the best gynaecologists in Mumbai, Dr. Neelima Mantri, we aim to improve awareness about the HPV vaccine by answering the most frequently asked questions. Read on to know:
What is the HPV virus?
The HPV virus, or human papillomavirus, is a common sexually transmitted infection. This virus can infect the mouth, genital area, and throat of both men and women. There are many different types of human papillomavirus, which can cause various symptoms, ranging from genital warts to cancers, including cervical, vaginal, penile, anal, and throat cancers. Other symptoms of infection caused by the HPV virus include itching, burning, or discomfort in the genital area, abnormal vaginal bleeding, and even pain during sex.
How is the HPV virus transmitted?
“HPV is primarily transmitted through sexual contact, including oral, vaginal, and anal sex. The virus spreads even if an infected person shows no signs or symptoms. HPV may also be passed from mother to baby during childbirth,” says female gynaecologist in Mumbai Dr. Neelima Mantri.
How does the HPV vaccine work? What types of cancers does it help prevent?
Like the majority of vaccines, HPV vaccines work by exposing the body to inactive forms of the virus. This way, our body gradually develops immunity against the virus in its active form when exposed. Cervical cancer, vaginal cancer in women, and anal cancer and oropharyngeal cancer (back of the throat) in both men and women are some of the cancers whose risk can be significantly reduced by getting the HPV vaccine.
How many doses of the HPV vaccine are needed for an individual? Is it safe?
The total number of doses required by the individual depends on the age at which they are vaccinated. Children and teens between ages 9 and 14 will require two doses of HPV vaccine over a 6-12 month period. If the HPV vaccine is administered between the ages of 15 and 26, three doses of vaccine will be required over a 6-month period. HPV vaccine is one of the most extensively studied vaccines and the most effective one with excellent efficacy rates in reducing the risk of HPV-related cancers. So yes, it is safe and effective for men and women.
What are the side effects of the HPV vaccine? Every vaccine shows a few mild side effects. In the case of HPV vaccine, the side effects are mild and often go away within a few days. The side effects of HPV vaccines may include pain, redness, swelling, dizziness, and in very rare cases, fainting.
Where can I get the HPV vaccine in India?
Government Health Centers, Private Hospitals, and Clinics are some of the primary sources of HPV vaccination. Even women’s health specialists or gynaecologists can also help you get the HPV vaccine in India. If you are in Mumbai, you can contact leading gynaecologist Dr. Neelima Mantri for HPV vaccination. You can contact her here.
